A mutant protein found in nearly all pancreatic cancers plays a role not only in the cancer's development but in its continued growth, according to a new study from University of Michigan Comprehensive Cancer Center researchers.
Researchers at the University of Michigan, led by Max Wicha, M.D., have found that Avastin, Sutent increase breast cancer stem cells. This could explain the limited success of anti-angiogenesis treatments in breast cancer.
Pavan Reddy, M.D., associate professor of hematology/oncology at the U-M Medical School, was the senior researcher who discovered alpha-1-antitrypsin -- a natural enzyme -- reduces intense inflammation after bone marrow transplant.
In a new study, a program known as Spatially Invariant Vector Quantization (SIVQ) separated a malignancy from background tissue in digital slides of a type of bladder cancer whose features can vary widely and presents diagnostic challenges even for experts.
Kathleen A. Cooney, M.D. of the University of Michigan Comprehensive Cancer Center, led this research effort which may may provide clues on prostate cancer development and who may need earlier screening.