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The mass spectrometry-based Proteomics Resource Facility (PRF) at the Department of Pathology assists researchers in designing proteomic experiment, maintain state-of-the-art instrumentation, provide technical expertise and bioinformatic support during both discovery and validation phases of proteomic experiments.


  • Peptide and protein identification
  • Analysis of protein-protein interactions and complexes
  • Shotgun proteomic profiling
  • Post-translational modifications analysis
  • Protein quantification and differential expression analysis using labeling and label-free approaches
  • Targeted quantification of selected peptides and proteins of interest

Major Equipment

  • Orbitrap Fusion (with ETD) mass spectrometer
  • Q Exactive HF mass spectrometer
  • UPLCs for peptide and protein separation

Learn more about Proteomics Resource Facility
If you have more questions about services at the PRF, contact our team or visit the Mass Spectrometry-Based Proteomics Resource Facility.

Director: Alexey Nesvizhskii, Ph.D.

Manager: Venkatesha Basrur, Ph.D.

Location: Rm 4204 Med Sci I
Phone: 734-615-5722